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Future research should focus on validating these benefits in human trials and developing optimized formulations for clinical application

Numerous research have been published in recent years that demonstrate the effectiveness of -tocopherol in cell signaling and gene regulation processes as both a pro- and antioxidant [139,140,141]

Its ability to activate sirtuins, enhance DNA repair, regulate metabolism, influence fat cell metabolism in preclinical models and support mitochondrial health positions it as a compelling candidate for further investigation

The amino acid sequence of rat liver G6PD shows 94% homology to the human sequence and provides evidence that the N-terminal amino acid is N -acetylalanine, which must result from posttranslational cleavage of the N-terminal methionine